The news that a famous Hollywood actress AngelinaJolie that she deleted herself ovaries and fallopian tubes, produced the result of a bomb explosion around the world. Artist dared on this step as a preventive against cancer.
But the researchers have criticized Jolie, calling her a bad role model. AngelinaJolie in 2013 find out about genetically determined risk of developing breast cancer and had surgery to remove the breast. This decision led to a strong effect of AngelinaJolie: in Britain alone, the number of ladies that have passed genetic diagnosis, increased in June-July by 250%.
However mutations in the genes BRCA1 and BRCA2 it is easy to detect. Much more uncertain is their effect on the development of malignant tumors. It turns out scientists have not collected the necessary data on the examined patients, with statistical confidence to prove such a causal relationship. These little-studied mutations are referred to as options a vague value. In consequence, scientists warn women from following the example of AngelinaJolie. The doctors said that mutations of the BRCA1 gene is not necessarily associated with dangerous disease.
At the same time, researchers collecting databases accessible to the public, come to the conclusion that many variants of undetermined significance BRCA absolutely harmless. "The more people on the planet are tested, the more we identify carriers of specific genetic mutations and variants of undetermined significance he goes into the category of not dangerous", - quotes genetics Katherine Nathanson from the Institute of Pennsylvania in Philadelphia, Nature News. Indeterminate results of genetic tests often force women to go for them worthless surgery (from the terror of cancer).
Earlier in the article for the newspaper The New York Times AngelinaJolie announced that cut the ovaries and fallopian tubes. "Last week I underwent surgery laparoscopic bilateral removal of the uterus. There was a small benign tumor on one ovary, but no symptoms of cancer in any other tissue", - said the actress.