The Muse rocker - whose girlfriend Kate Hudson is expecting their first child - says while he was single, he used to make made numerous trips to his home in Lake Como because the Italian women are "incredible".
Matt, 32, was approached by The Hurts guitarist Adam Anderson who asked: "I know your sh**ging days are over but you must have seen some action in your time with the band?"
The Muse frontman replied: "Oh I`ve had fun, a lot of fun. You go to Italy. The women there are incredible."
Before beginning his romance with Kate last year, Matt was engaged to Italian psychologist Gaia Poloni with the pair splitting in 2009.
Apart from Italian women, Matt also previously claimed he is just as charmed - although not as lucky - with older women too.
He said: "Jane Fonda. She`s 72. I like the older ladies, you see. She was hanging around with Rod Stewart the other day. She seemed like a nice lady. But I failed - I didn`t charm her enough."