The music mogul - who has his own record label Syco - is in the early stages of putting together a pop group to conquer the US market and has been in talks with a number of producers and songwriters to create the right sound.
A source told JustJared.com: "Simon is really excited to form a group of guys from America. He`s done such a fine job with British boys, so he`s ready to try his hand in America. He`s looking for the right people to team up with and create their sound."
Meanwhile, Simon`s UK and Irish boy band One Direction - who were formed on UK TV show `The X Factor` - are enjoying success in the US with their debut single `What Makes You Beautiful`, which has placed at 28 on the Hot 100 chart.
Their PR company Hackford Jones tweeted: "One Direction have debuted at No.28 in the US Hot 100 chart. It`s the highest US chart debut for a UK act in over 14 years."
The group, comprised of Niall Horan, Zayn Malik, Liam Payne, Harry Styles and Louis Tomlinson, have been making a name for themselves in America where recently filmed a guest appearance on Nickelodeon`s `iCarly` and are set to support Big Time Rush on tour.