Hans Adolf Krebs( English biochemist, awarded the 1953 Nobel Prize in Physiology or Medicine)
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Biography Hans Adolf Krebs
Krebs, Hans Adolf (Krebs, Hans Adolf) (1900-1981), English chemist, awarded in 1953 (jointly with F. Lippmann) Nobel Prize in Physiology or Medicine for his discovery of tricarboxylic acid cycle. Born August 25, 1900 in Hildesheim (Germany). He studied in GцTttingen, Freiburg, Munich, Berlin University (1919-1924). In 1924 received his medical degree at the University of Munich. In 1926-1930 he worked at OG Warburg at Berlin University. In 1931-1933 headed the Laboratory of Biochemical and taught at the University of Freiburg. With the advent of the Nazis, was dismissed from the university and went to England. Worked at Cambridge, Sheffield and Oxford. Since 1967 directed the laboratory to study the metabolism in the Royal Hospital in Oxford.
The main works are devoted to studying the Krebs metabolic processes (metabolism). In 1932 he opened a sequence of chemical reactions, during which the tissues of animals from ammonia formed by urea (urea cycle, or ornitinovy cycle). Studying the formation and transformation of citric acid in animal cells, . in 1937 proposed a cycle of eight reactions, . provides transformation (in the presence of oxygen) decomposition products of sugars, . fats and proteins into carbon dioxide, . water and high-energy compound adenosine triphosphate (ATP) - the energy 'depot' cells,
. This sequence of reactions, known as the Krebs cycle (or tricarboxylic acid cycle), is the basis of the oxidation of nutrients in animals.
In 1958, Krebs was elevated to the dignity of knighthood, in 1961 was awarded the Copley Medal.
Krebs died in Oxford on Nov. 22, 1981.