The 27-year-old socialite - who has been married to basketball player Lamar Odom for over two years - reportedly visited the ART Reproductive Center in Beverly Hills on 11.06.12 to discuss her options.
According to gossip website TMZ, Khloe took her sister Kim along for support where she gave blood so that doctors can evaluate her hormone levels and figure out a suitable treatment programme.
Khloe is thought to have been considering getting medical help since her sister Kourtney - who already has a two-year-old son Mason with her boyfriend Scott Disick - announced she is pregnant again and due this summer.
A source said: "She`s thrilled for Kourtney, but she`s really sensitive. And it`s hard to see your sister get something you want so badly."
The `Keeping Up with the Kardashians` star has previously admitted she feels under pressure to have a baby.
Speaking last year, she said: "People keep saying, `Why aren`t you pregnant yet?` That`s what scares me, when people are like, `Did you go to the doctor? Do you know if everything`s working?` It`s nerve-racking. Sometimes I feel like I`m letting everyone down."
Lamar already has two children, Destiny, 13, and 10-year-old Lamar Jr., from a previous relationship.