The `Lollipop` rapper and his crew were targeted by a man who put the substance into the air ducts of Montreal club La Mouche, where the hip-hop star was hosting an afterparty following his gig at the Bell Centre in Montreal on 17.08.11.
The ventilation system was compromised following the stunt, which caused everyone to be evacuated.
It is not clear whether the police are investigating the incident, but a representative for Wayne said the 28-year-old star was "okay and gearing for his next stop in Toronto."
Wayne - who was supported by `Your Love` hitmaker Nicki Minaj earlier this year - is set to continue his I Am Still Music summer tour at the Molson Amphitheater in Toronto, Canada, tomorrow evening (19.08.11).
`Like A G6` rappers Far East Movement and R&B crooner Lloyd have been opening the rapper`s recent gigs, which have seen him supported by `Pretty Girl Swag` singer Keri Hilson after she replaced Nicki.
Wayne is set to finish his tour on September 11 at the Woodlands Amphitheater in Texas.