The `Scream` actress and her partner JJ Feild confirmed they were expecting through their representative, who said "they are thrilled" to be expanding their family.
It is not known when she is due to give birth.
Canadian beauty Neve will have plenty of experience being a mother, claiming she felt like a parent on the set of new film `Scream 4` because many of the new cast, including Rory Culkin, Emma Roberts and Hayden Panettiere, were so young.
The 38-year-old star said: "Those kids were five when the first `Scream` came out, so I hope to God their parents weren`t letting them watch it.
"Courteney Cox and I just looked at each other and were like, `We could be their mothers.` "
Neve is currently filming the role of Kate Burkholder in `Sworn to Silence`, which is due out later this year, and recently completed work on `Titanic: Blood and Steel` alongside Derek Jacobi and Kevin Zegers.
JJ is best known for his role as Union Jack in `Captain America: The First Avenger`.