The `Descendants` actor is selling his 2008 Tesla Signature 100 Roadster to raise funds for relief work in Sudan, with the electric vehicle - which has just 1,700 miles on the clock - expected to fetch up to $125,000.
The car - one of the earliest models of the two-seater sports car - will be auctioned off by Gooding & Company at the Pebble Beach Concours d`Elegance in Los Angeles on August 19.
David Gooding, president and founder of the auction company, said: "We are overjoyed to present GeorgeClooney`s Signature 100 Tesla at Pebble Beach because this is an incredible opportunity to purchase a modern collector car with all the right elements; one-owner, celebrity provenance; historical significance; limited-edition rarity and philanthropic ties."
Proceeds from the sale will benefit the Satellite Sentinel Project, which was co-founded by George and activist John Prendergast and uses satellite pictures to monitor the Sudanese region for evidence of "alleged atrocities".
George has long been outspoken about the humanitarian crisis in Sudan and in March, he was arrested with his father and members of congress outside the country`s embassy in Washington for protesting about human rights abuse.
He was released from jail the same day he was arrested after posting $100 in bail.