SEYBIN Albert Bruce (Sabin Albert Bruce)

(1906-1993)
Born August 26, 1906 in Bialystok (Russia, now Poland). In 1921 his family moved to the U.S.. He studied at New York University, in 1928 received a bachelor's degree in 1931 - the degree of Doctor of Medicine. He worked at Bellevue Hospital (New York), then in Listerovskom Institute of Preventive Medicine in London, from 1935 - at the Rockefeller Institute for Medical Research (New York). In 1939 he was invited to the post of professor at the Department of Pediatrics Medical College, University of Cincinnati and director of the department of infectious diseases at Children's Hospital at the University of.
The main works Seybina devoted to polio. 1931 Seybin demonstrated the growth of poliovirus in human nervous tissue in vitro. In 1941, showed that the virus primarily infects the digestive tract. During the Second World War Seybin served in the U.S. Army Medical Corps. To develop vaccines against dengue fever and Japanese encephalitis. After the war started to create a vaccine against polio. Regardless of him over the same problem worked Dzh.Solk from the University of Pittsburgh. Seybin believed that a vaccine based on live, but nevirulentnoy form of the virus would be more effective than the inactivated Salk vaccine, created by the last in 1954. Vaccine Seybina appeared in 1956. In 1957 Seybin identified strains of all three types of polioviruses, and received the appropriate vaccine. In the United States permission to use the vaccine Seybina was given only in 1961. Widespread use of vaccine is found in Russia and some European countries. Died Seybin in Washington March 3, 1993.